Learn more about the research of Mayo Clinic's Gene Editing and Cellular Engineering Laboratory led by David (Chun-Wei) D.

Acute myeloid leukemia (AML) is an aggressive cancer affecting the blood and bone marrow that progresses rapidly, making immediate treatment essential. While chemotherapy and targeted drugs have ...

Researchers have developed a peptide that targets a protein implicated in 75% of human cancers and found that it slowed the proliferation of cancer cells in the lab. It’s the first step towards ...

For example, myc function can be inhibited by protein p107. However, mutations in the N-terminal region of myc can inhibit the p107 from performing its inhibitory effect, leading to activation of myc.

They found that a protein called RBM10 can partner with other proteins to stop c-Myc activity, which is a tumor-stimulating protein that causes lung cancers. U.S. World ...

FAST kinase domain-containing protein 5 (FASTKD5) is a mitochondrial protein that is needed for processing mRNA in the primary mitochondrial transcript. Several mutations have been found in other ...

Like any protein, MYC is built using the instructions that are stored in the MYC gene. First, in a process called transcription, the cell uses these instructions to make a blueprint, called mRNA.

Hollow spheres made of MYC proteins open new doors in cancer research. Würzburg scientists have discovered them and report about this breakthrough in the journal "Nature".

A gene called MYC is implicated in the majority of cancers, but unfortunately it’s often considered “undruggable.” In a new study scientists have developed a molecule that chops up the RNA ...