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They found that a reduction in Myc caused a similar reduction in the levels of CD47 and PD-L1 proteins on the surface of mouse and human acute lymphoblastic leukemia cells, mouse and human liver ...
Researchers have developed a peptide that targets a protein implicated in 75% of human cancers and found that it slowed the proliferation of cancer cells in the lab. It’s the first step towards ...
An antibody that recognizes both the endogenous mouse Myc and transgenic human MYC proteins was used to determine the levels of MYC protein; antibodies against β-actin were used as a loading control.
Like any protein, MYC is built using the instructions that are stored in the MYC gene. First, in a process called transcription, the cell uses these instructions to make a blueprint, called mRNA. Then ...
Like any protein, MYC is built using the instructions that are stored in the MYC gene. First, in a process called transcription, the cell uses these instructions to make a blueprint, called mRNA.
Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells. Researchers have found that MYC protein may affect circadian ...
A gene called MYC is implicated in the majority of cancers, but unfortunately it’s often considered “undruggable.” In a new study scientists have developed a molecule that chops up the RNA ...
Hollow spheres made of MYC proteins open new doors in cancer research. Würzburg scientists have discovered them and report about this breakthrough in the journal "Nature".
The protein produced by the MYC oncogene is a well-known foe in the oncology world. Its presence is associated with treatment-resistant cancer cells, which grow uncontrollably and evade the immune ...
Degradation is a therapeutic strategy that could offer possibilities to get at currently undruggable target proteins. In ...
They found that a protein called RBM10 can partner with other proteins to stop c-Myc activity, which is a tumor-stimulating protein that causes lung cancers. U.S. World ...