Typically, magnesium exists as the Mg 2+ ion. It is present in all cells in all organisms from plants to higher mammals and is indispensable for health and life because it is an essential cofactor ...

As reported in this issue, Kern and co-workers 7 have studied the role of a magnesium (Mg 2+) cofactor in the Adk cycle, which catalyzes the reversible phosphorylation of AMP by ATP.

To make the system work, the researchers designed new versions of glucose dehydrogenase, an important partner for the cofactor. Their engineered version has more electrostatic interactions with ...

More information: Zehui Guo et al, Peptide bridging for cofactor channeling in fusion enzyme lowers cofactor input by two orders of magnitude, Chinese Journal of Catalysis (2025). DOI: 10.1016 ...

Cofactor Genomics has announced an $18 million Series A financing round led by Menlo Ventures, with participation from DCVC, Ascension Ventures, iSelect, Y Combinator, Wilson Sonsini Goodrich ...