This conversion of GTP to GDP at microtubule tips speeds up both their polymerization and depolymerization, collectively known as MT "dynamic instability," which facilitates its growth or breakdown.

The authors followed individual XMAP215 molecules during microtubule polymerization and measured a mean residence time of almost 4 seconds, during which time the microtubule grew by ∼0.2 μm ...

This conversion of GTP to GDP at microtubule tips speeds up both their polymerization and depolymerization, collectively known as MT “dynamic instability,” which facilitates its growth or ...