Selective autophagy of mitochondria, known as mitophagy, is an important mitochondrial quality control mechanism that eliminates damaged mitochondria. Mitophagy also mediates removal of ...

In the study, as a starting point for their investigation of the link between mitochondrial calcium transport and autophagy, the researchers submitted mice to four months of calorie restriction ...

The research team investigated the mechanism underlying the mitochondrial number reduction, with a special focus on autophagy. Autophagy degrades cellular components, including the organelles, by ...

The ability of molecules to pass through the membrane of mitochondria -- the cellular structures that convert nutrients into energy -- may determine whether or not autophagy, a cellular process ...

Ever feel like your body needs a "deep clean"? Like your cells are screaming to get rid of all the old and damaged stuff to work better? Well, let me tell you something incredible!

They discovered that in budding yeast adapting to respiratory growth, autophagy ... Feb. 13, 2025 — A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy.

Mitochondria fuse and divide in response to cell demands and ... Dagda, RK, Tandon, A, Chu, CT. Mitochondrial autophagy as a compensatory response to PINK1 deficiency. Autophagy 2009;5:1213-1214.

Mc-mitochondria exhibit superior performance for in vivo mitotherapy. ... Remarkably, cells undergoing this process downregulated energy-intensive activities like autophagy and secretion, ...

The study elucidated a chain event that explains how and why impaired autophagy can lead to cardiac dysfunction. The first step of this chain is the accumulation of a protein known as SQSTM1.