Pathways of hepatocyte apoptosis Mitochondria are central to the regulation of apoptosis, the programmed cell death process, which plays a pivotal role in cholestatic liver injury.

Qtn-PVPylated-TiO 2 NPs uptake via endocytosed by cancer cells able to generate intracellular ROS, to decrease the mitochondrial membrane potential loss (Δψm) to release cytochrome- c, Bcl-2 ...

The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases.

BAKX Therapeutics is a New York and Boston based company focused on developing safer, more effective therapeutics that fully realize the potential of the mitochondrial apoptosis pathways.