Researchers report that failure of autophagy may be a central mechanism in the pathogenesis of focal segmental glomerulosclerosis (FSGS). Jeremy Duffield and colleagues showed that abrogation of ...

Dysfunction of autophagy — an intracellular degradation pathway for cytosolic material — has been implicated in the pathogenesis of various neurodegenerative diseases. Rubinsztein and ...

In the study, as a starting point for their investigation of the link between mitochondrial calcium transport and autophagy, the researchers submitted mice to four months of calorie restriction ...

Motor neurone disease (MND) is a rare but progressive neurological disorder characterised by the degeneration of motor ...

A new study sheds light on how autophagy, the body’s process for removing damaged cell parts, when impaired, can play a role in causing heart failure.

A cohort of eight babies at risk of inheriting mitochondrial disease were born without complications after British scientists ...

Autophagy, the process by which cells recycle damaged components, has long been associated with neuroprotection. However, the ...

The study elucidated a chain event that explains how and why impaired autophagy can lead to cardiac dysfunction. The first step of this chain is the accumulation of a protein known as SQSTM1.

Mitochondrial dysfunction is the root cause of many diseases. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2017 / 01 / 170126093255.htm ...

Researchers report that eight healthy babies were born with the help of an experimental technique that uses DNA from three ...

More information: Qiudan Luo et al, The interaction between microglial dysfunction and mitochondrial impairment in Alzheimer's disease, Aging Research (2024). DOI: 10.26599/AGR.2023.9340020 ...