One of the greatest revolutions in the field of pain medication was the isolation of morphine from the opium poppy in the ...

PBAE mapping and model validation. (A) Molecular structure and pKa values at 25 °C of the PBAE copolymer with spermine (left) and oleylamine (right) subunit.

Chemical structures called cyclopropanes can increase the potency of many drugs, but traditional methods to create this structure require highly reactive -- potentially explosive -- ingredients.

Researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs. ... (2024, November 27). Drug research: Decoding the structure of nano 'gene ferries'.

This study revealed the molecular mechanism by which ABCC4 recognizes broad-spectrum substrates, and provided a structural basis for the rational design of platelet antagonists targeting ABCC4 and ...

The COVID pandemic illustrated how urgently we need antiviral medications capable of treating coronavirus infections.

When that was replaced by a short linker, the researchers were able to determine a 3.0 Å cryo-electron microscopy structure of the truncated MmpL4. Besides their normal role, pump overexpression ...

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to ...