We provide evidence that the p3-mediated specific cleavage activity of active caspase-3 abrogated the function of the NES. ... (Sigma), and then with FITC goat anti-mouse IgG ...

Interestingly, tau is a known caspase-3 substrate, and caspase-cleaved tau fragments readily form neurofibrillary tangles (see de Calignon et al., 2010). A Slow Death. In this model, increasing ...

At the same time, ICW results showed that cleaved caspase-3 level increased significantly in all of the nine responsive cell lines, but not in the two nonresponsive cell lines. Furthermore, among the ...

Lina Y. Abou Zeid, Shanmugapriya Shanmugapriya, Rebecca L. Rumney, Dick D. Mosser, Caspase-mediated cleavage of miRNA processing proteins Drosha, DGCR8, Dicer, and TRBP2 in heat-shocked cells and its ...