The bacterium that causes tuberculosis has a unique molecule on its outer cell surface that blocks a key part of the body's defense. New research suggests this represents a novel mechanism in the ...

New drugs that target "zombie" tuberculosis (TB) cells are now a step closer, thanks to a new study led by the University of ...

Chemists found a way to identify a complex sugar molecule in the cell walls of Mycobacterium tuberculosis, the world's deadliest pathogen. This labeling could lead to simpler, faster TB tests.

News Release 25-Oct-2012 Structure discovered for promising tuberculosis drug target M. tuberculosis cell wall could soon be breached Peer-Reviewed Publication Johns Hopkins Medicine ...

Called "Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis," their work involves characterizing the enzymes using the UK's national synchrotron, Diamond ...

M. tuberculosis has a unique cell wall structure composed of mycolic acids, contributing to its potential to become resistant to certain antibiotics. This can make treating TB difficult.

Although current TB vaccine strategies are largely aimed at activating conventional T-cell responses to mycobacterial protein antigens, the lipid-rich cell wall of Mycobacterium tuberculosis is ...

Suicide system present in the genome of tuberculosis (TB) bacterium, Mycobacterium tuberculosis (Mtb), is one of the top ten killers globally. This unique suicide system, known as toxin-antitoxin ...

Unfortunately, clinical Mycobacterium tuberculosis strains rapidly become resistant to bedaquiline, predominantly by overexpression of MmpL5. The proteins MmpL5 and MmpL4 are efflux transporters, ...