Some mutant animals with defects in myelin proteins and lipids have been discovered or generated, providing useful disease models for hereditary demyelinating disorders. Further research is ...

View Full Profile. Learn about our Editorial Policies. Insufficient myelination, likely caused by a lack of mature oligodendrocytes, is linked to autism spectrum disorder, according to a study in mice ...

The research suggests the role of CD11c-positive microglia—immune cells in the brain crucial for myelination—during infant brain development. The results, published in Communications Biology ...

The thyroid hormone thyroxine, or FT4, plays an indirect role in the development of MS that seems to be mediated by certain ...

Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and stability of myelin, suggesting an important impact on neurodegenerative diseases ...

The researchers concluded that "myelin seems to act as an energy source when other brain nutrients are depleted during endurance exercise, and that further research is needed to establish how ...

in the formation and stability of myelin, suggesting an important impact on neurodegenerative diseases and mental disorders such as multiple sclerosis and schizophrenia. The findings pave the way ...

Myelin and Mental Efficiency The fatty sheath ... White matter in learning, cognition and psychiatric disorders. Trends in Neurosciences, 31(7), 361–370. Montague, P. R., ...

Similarly, we found that molecules such as integrins and RhoGTPAses are required for glia to extend large processes that will become myelin around axons. In certain neuromuscular disorders, defective ...

More information: Kazuya Fuma et al, Prenatal inflammation impairs early CD11c-positive microglia induction and delays myelination in neurodevelopmental disorders, Communications Biology (2025).

in the formation and stability of myelin, suggesting an important impact on neurodegenerative diseases and mental disorders such as multiple sclerosis and schizophrenia. The findings pave the way ...