One of the greatest revolutions in the field of pain medication was the isolation of morphine from the opium poppy in the ...

Chemical structure of (-)-naloxone and (+)-naloxone enantiomers. Ki of (-)-naloxone for antagonizing opioid receptors is in the 1 nM range whereas (+)-naloxone has a very low affinity for opioid ...

Kohane’s team created the nanoparticles by attaching molecules of naloxone to a polymer considered safe for humans, rendering the medication temporarily inert. The connection between naloxone and the ...

In Fig. 1b, a double bond is missing in the structures of heroin, 6-acetylmorphine and morphine. In Fig. 1c, the N-alkyl group is one carbon too short in the naloxone methiodide structure.

Researchers published a study in ACS’ Nano Letters involving injectable naloxone that would treat overdoses by releasing the drug on demand, triggered by light.