Hyderabad: Suven Life Sciences has announced that the first patient has been randomized in its Phase-2b clinical trial ...

Suven Life Sciences announced that the first patient has been randomized in its Phase-2b clinical trial evaluating Ropanicant, a novel oral α4β2 nicotinic acetylcholine receptor (nAChR) antagonist, ...

A role for β2* nicotinic receptors in a model of local amyloid pathology induced in dentate gyrus. Neurobiology of Aging , 2016; 46: 221 DOI: 10.1016/j.neurobiolaging.2016.06.005 Cite This Page : ...

Nicotinic receptors, such as the α7 subtype, are at the apex of key cellular pathways, both central and peripheral, and are involved in anti-inflammatory processes, as well as cell survival.

Preliminary scientific report. Oliveira, A.S.F. et al. (2020). Simulations support the interaction of the SARS-CoV-2 spike protein with nicotinic acetylcholine receptors and suggest subtype ...

Receptors known as "α7 nicotinic receptors" acts as a switch that can reduce inflammation. When activated by nicotine, these receptors suppress the production of inflammatory molecules.

Autoantibodies specific for nicotinic acetylcholine receptors in the autonomic ganglia are potentially pathogenic and may serve as serologic markers of various forms of autoimmune autonomic ...

11 Jul 2009. The α7 nicotinic acetylcholine receptor (α7nAChR) binds the amyloid-β peptide (Aβ) with high affinity (Wang et al., 2000), and has been implicated in Aβ internalization, stimulation of ...