Normal phase HPLC is a valuable technique for the separation of polar and hydrophilic compounds and for isomer separation. Normal phase HPLC requires a polar stationary phase combined with non or ...

In HPLC, separation is based on hydrophobic interactions (reversed phase HPLC) or hydrophilic interactions (normal-phase HPLC) of the analytes with the stationary phase.

The company has demonstrated chiral SFC separations that require one-thirtieth the time compared with standard normal-phase HPLC. Solvent consumption and lower cost are additional benefits.

These are generally conventionally acquired with GC, GC/MS, or normal-phase HPLC, which are slow and of limited sensitivity. On the UPLC MSE set up, at high temperatures, ...

The normal-phase HPLC method diluent utilized a mixture of THF and hexane. As such, the HPLC diluent was a preferred solvent option for the anhydrous forced-degradation solution conditions. Another ...

With years of experience in the pharmaceutical and life science sector, CD Bioparticles has launched a range of monodisperse, porous, high-purity nomal-phase chromatography resins, with diameters of 1 ...

Depending on the mechanism of action, various HPLC techniques such as adsorption chromatography, partition chromatography (normal phase, reversed phase), ion exchange chromatography, affinity ...

For normal phase HPLC separation, a Zorbax NH 2 column (250 mm × 4.6 mm) was used for analysis and a semi-preparative Zorbax NH 2 column (250 mm × 9.2 mm) was used for preparative separations.

Following the HPLC method (normal phase) described in the US PF, 4 we detected at the reported RR t values the presence of tautomers I and II and the presence of derivative 5.