Notch signaling pathway keeps immature T cells on the right track. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2013 / 11 / 131122165451.htm ...

Cut off any part of this worm's body and it will regrow. This is the spectacular yet mysterious regenerative ability of ...

Because the Notch signaling pathway is very similar in mice and humans, Kuang sees the results as having important implications for treating obesity and Type 2 diabetes in humans. Type 2 diabetes, ...

One protein called Notch, which has well-known roles in the development of multiple tissues, plays an essential role in triggering T-cell development. Notch signaling induces expression of genes ...

The Notch signaling pathway, present in insects, worms and vertebrates, is involved in embryonic patterning as well as nervous system and cardiovascular development.

The Notch signaling pathway is central to a wide array of developmental processes in a number of organ systems, including hematopoiesis, somitogenesis, vasculogenesis, and neurogenesis. These ...

Recent studies have revealed that the Notch signaling pathway is important for esophageal epithelial homeostasis 42 and development of Barrett's adenocarcinoma. 43 Further research is required for ...

A cell signaling mechanism of fundamental importance to animal development is the Notch pathway (Figure 1). It may be safely said that Notch signaling is required, in some reasonably direct fashion, ...

NOTCH signaling influences these traits through interactions with other pathways like TGF-β, WNT, and hypoxia signaling. The canonical NOTCH pathway maintains resistant cell populations, while ...

The notch signaling pathway plays a major role in regulating various cellular processes during development, therefore dysregulation of this pathway can lead to disease.

EPFL spin-off Cellestia Biotech has just been given the regulatory go-ahead to start clinical testing a molecule it has developed to treat cancers involving mutations of the Notch gene. The ...

Nature is thrifty. The same signals that embryonic cells use to decide whether to become nerves, skin or bone come into play again when adult animals are learning whether to become afraid.