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This review focuses on the unique characteristics of mitochondrial nucleoids in mammalian cells, highlighting their ...
Mitochondrial DNA is organized into dynamic, dot-like structures called nucleoids. Researchers have recently revealed new insights into how the nucleoids move around.
Nucleoid-associated proteins (NAPs) bind to the bacterial chromosome and alter its dynamics, maintaining nucleoid structure. In this Review, Dillon and Dorman examine the range of proteins in the ...
Regulation of nucleoid dynamics is crucial for the maintenance of respiratory chain complexes on the mitochondrial inner membrane, and this is the first report of the role of ATAD3A in ...
“Nucleoid trafficking may represent a new therapeutic target to prevent mitochondrial dysfunction in various human diseases,” explains senior author Naotada Ishihara.
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