In contrast, the myelin-forming cells in the brain and spinal cord, oligodendrocytes, lack these properties, which helps explains why the CNS has such a limited ability to fix damaged nerves.

Schwann cells can produce myelin around a single axon in the peripheral nervous system while the oligodendrocytes work on multiple axons at once in the brain and spinal cord to protect them with ...

Both Schwann cells and oligodendrocytes arose at the same point in evolutionary history, ... To create myelin, Schwann cells evolved to produce it around a single axon in the peripheral nervous ...

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves. The Journal of Cell Biology , 2015; 210 (1): 153 DOI: 10.1083/jcb.201503019 Cite This Page : ...

Myelin-making Schwann cells have an ability every aging Hollywood star would envy: they can become young again. According to a study appearing in the May 19 issue of the Journal of Cell Biology ...

To create myelin, Schwann cells evolved to produce it around a single axon in the peripheral nervous system. Oligodendrocytes, in turn, generated myelin along multiple axons within the more ...

Unlike Schwann cells, oligodendrocytes, the myelin makers in the central nervous system, can’t revert to an immature state. Whether c-Jun affects oligodendrocyte differentiation isn’t known. ### ...

Until now, scientists thought that only oligodendrocytes generated multiple myelin sheaths around axons, the slender projection of a nerve cell that carries electrical signals between cells. The new ...

Oligodendrocytes and Schwann cells contain no glycogen. ... Yin, X. et al. Evolution of a neuroprotective function of central nervous system myelin. J. Cell Biol. 172, 469–478 (2006).

In the brain and spinal cord, myelin is created by cells called oligodendrocytes. These octopus-looking cells have a cell body and several extensions growing off in all directions.

How oligodendrocytes use fatty acid metabolism as an energy reserve to maintain axonal function and myelin stability when glucose is scarce, offering insights into neurodegenerative disease ...

In discovering how Schwann cells generate myelin at the molecular level, the discovery may lead to new gene-therapy techniques to repair damaged myelin in peripheral nervous system disorders such ...