Phospholipase A2 Inhibition as Potential Therapy for Inflammatory Skin Diseases. ... The prospect of PLA 2 inhibition for treating skin inflammation has been demonstrated in previous studies using ...

Twelve weeks of treatment with the phospholipase A2 inhibitor LY333013 may be ineffective as an adjunct to DMARDs in active RA. (Bradley JD et al. 2005; 32:417-423.) ...

Phospholipase A2 (PLA2) ... Furthermore, innovative research into arachidonic acid analogues has demonstrated potent inhibition of cytosolic PLA2, ...

Together with available clinically tested sPLA2-IIA inhibitors, ... J.M., et al. (2021) Group IIA secreted phospholipase A2 is associated with the pathobiology leading to COVID-19 mortality.