A protein-engineering strategy, in which a constitutively active form of an immune receptor is kept inactive by a peptide ...

Rhomboid proteases are a promising target for new drugs. Now researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have uncovered a mechanism for regulating enzyme ...

To pinpoint the enzyme responsible, Cann and his team used the lysate of an E. coli strain lacking each of the proteases to feed live cells. While dead cells lacking OmpT enhanced live cell growth, ...

CHAMBERED PROTEASE. A multi-subunit proteolytic enzyme that has a barrel-shaped structure and sequestered active sites. It is sometimes called a compartmentalized or self-compartmentalized protease.

Researchers from DZNE, Ludwig-Maximilians-Universität München (LMU), and Technical University of Munich (TUM) have found that ...

The Pfizer compound was developed to inhibit an enzyme called a protease. The revived compound is specific to the proteases produced by coronaviruses, which are responsible for causing SARS in ...

A team of researchers at the Department of Energy's Oak Ridge and Argonne national laboratories has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease -- the ...

This key enzyme cleaves 11 sites on the large viral polyprotein, ... Study finds atazanavir inhibits main SARS-CoV-2 protease. News-Medical, viewed 16 February 2025, https: ...

Scientists at UC Davis discovered a small genetic difference that could explain why humans are more prone to certain cancers than our primate cousins. The change affects a protein used by immune cells ...

The main enzymes produced by the pancreas are amylase, which breaks down complex carbohydrates; lipase, which digests fats; and proteases, which break down fats. The enzymes lactase and sucrase ...