Rhomboid proteases are a promising target for new drugs. Now researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have uncovered a mechanism for regulating enzyme ...

Protease profiling using DNA microarray chips provides a general view of the protease transcriptome, but messenger RNA expression levels do not reflect protease protein abundance or activity ...

This study demonstrated that the subtilisin-like protease from recombinant P. pastoris strains exhibits proteolytic activity, which depends on the incubation time and the choice of signal peptide ...

“Biochemical Characterization of Protease Activity of Nsp3 from SARS-CoV-2 and Its Inhibition by Nanobodies.” Edited by A Ganesan.

More information: Fangfang Lu et al, Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals, Molecular Cell (2024).

A new assay rapidly detects pancreatic ductal adenocarcinoma and differentiates it from noncancer pancreatic diseases by measuring cancer-associated protease activity in a small amount of blood.

Why do some people feel itchy after a mosquito bite or exposure to an allergen like dust or pollen, while others do not? A new study has pinpointed the reason for these differences, finding the ...

Proteases in the insect midgut have been associated with differences in susceptibility to Bacillus thuringiensis (Bt) insecticidal toxins. Therefore, we evaluated the protease activity of laboratory ...

Alpha-1-antitrypsin is a so-called protease inhibitor, a type of enzyme inhibitor. It is produced in the liver but exerts its ...

To investigate the mechanism by which MG-101 inhibits the activity of Mpro protease, the scientists, including Manju Narwal, postdoctoral scholar in biochemistry and molecular biology, used X-ray ...

Study: Main protease mutants of SARS-CoV-2 variants remain susceptible to PF-07321332. Image Credit: Kateryna Kon/Shutterstock This news article was a review of a preliminary scientific report ...