This in-cell NMR protocol allows the study of protein folding and maturation in the presence of cofactors in cultured mammalian cells.

PROTEUS, a system designed to harness “directed evolution,” can speed the process up by years, or even decades.

Fluorescent proteins are widely used in molecular biology to visualize protein expression and localization. Here, Krizet al. describe an efficient and flexible modular plasmid-based eukaryotic ...

Plant molecular farming (PMF) is a modern, sophisticated technology that utilizes plants' biosynthetic machinery to ...

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living ...

Figure 1. Core concept of recombinant protein expression and common host cells. PTM= post-translational modification. Image Credit: Sino Biological Inc. Challenges in recombinant protein ...

Researchers have developed a novel method for controlling the precise amount of protein produced by mammalian cells. A recent research effort from the Massachusetts Institute of Technology (MIT; MA, ...

Researchers developed an RNA-based switch, the pA regulator system, to control gene expression in mammalian cells by modulating synthetic polyA signal cleavage, offering a novel approach for gene ...

Integrating best practices in AI, genomics, cell culture, and laboratory techniques together contribute to protein expression success.

Researchers have developed a new way to deliver molecular therapies to cells. The system, called SEND, can be programmed to encapsulate and deliver different RNA cargoes.

It is true that mammalian cells have the ability to incorporate foreign substances through endocytosis. But this by no means guarantees transport to the desired site of action.

Understand Efficient Expression Strategies: Learn the latest techniques and approaches for optimizing the expression of membrane proteins, including vector design, host selection, and expression ...