Researchers from Helmholtz Munich and the Technical University of Munich have developed a novel method to track cancer ...

Proteins are the building blocks of life. They consist of folded peptide chains, which in turn are made up of a series of ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in ...

As discussed already, misfolded proteins result when a protein follows the wrong folding pathway or energy-minimizing funnel, and misfolding can happen spontaneously.

Here, researchers describe a general concept that links protein folding and misfolding: protein folding and amyloid formation are separated by the supersaturation barrier of a denatured protein.

A large number of illnesses stem from misfolded proteins, molecules composed of amino acids. Researchers have now studied protein misfolding using a special spectroscopic technique. Misfolding is ...

Tauopathies are neurodegenerative diseases driven by tau protein misfolding and subsequently accumulating into dense, ordered fibrils. These tauopathies are prion-like, meaning that misfolded tau ...

Researchers from Osaka University have described the link between accurate protein folding and misfolding that can lead to the formation of amyloid fibers, which are implicated in ...

It's commonly accepted that protein folding/misfolding are alternative reactions of unfolded proteins but the principles governing this remain unknown. Here, researchers from Osaka University ...

Future directions and challenges in protein misfolding research New drugs are actively being sought for the treatment of neurodegenerative diseases related to protein misfolding and aggregation.