In a new study, Nobel laureate David Baker and colleagues detail new methods for targeting undruggable "disordered" proteins.

Think back to that basic biology class you took in high school ... Ever since scientists first got a good look at the ...

Protein folding and its opposite, protein unfolding, are exactly what they sound like – the very structure of a protein folds in upon itself, forming a unique shape. Once you view proteins on a more ...

In a finding that offers fresh insights into the early evolution of life on Earth, two RIKEN biologists have conducted lab ...

An AI called AlphaFold predicted structures for nearly every protein known to science. Those predictions aren’t without limits, some researchers say.

There’s an age-old adage in biology: structure determines function. To understand the function of the myriad proteins that perform vital jobs in a healthy body—or malfunction in a diseased one ...

The ultimate aim of structural genomics is not to obtain the structures or models for all proteins, but to contribute to biology and medicine through functional annotation 4,5,6,7, and through ...

AlphaFold solved a structural biology riddle: predicting protein structure. And yet, CASP, a global competition born to solve that problem, lives on.

Over the past two years, machine learning has revolutionized protein structure prediction. Now there's a similar revolution in protein design. Biologists show that machine learning can be used to ...

This means that the hydrophobic repulsive force stabilizes the folded protein structure. ... (2021, October 4). Restructuring biology: New study shows protein hydrophobic parts do not hate water.

The prediction of protein structure with the use of artificial intelligence and machine learning (AI–ML) is poised to transform how and when three-dimensional (3D) biostructure information is ...