The nonreceptor, protein-tyrosine kinase Syk is a suppressor of breast cancer progression whose expression is inversely correlated with the invasive behavior of cancer cells. In contrast, Syk has ...

Oncogene - Bcr-Abl protein tyrosine kinase activity induces a loss of p53 protein that mediates a delay in myeloid differentiation Skip to main content Thank you for visiting nature.com.

Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective. Signal Transduction and Targeted Therapy, [online] 7(1).

Src kinase is a multifunctional intracellular tyrosine kinase which has been implicated in the regulation of a variety of physiological and oncogenic processes such as proliferation, differentiation, ...

The fusion is known to cause the expression of three altered forms of tyrosine kinase proteins (BCR-ABL proteins): p210, p230, and p190, each of which is always “on”, and can go on to ...

Another new target in tyrosine kinase development is protein kinase B (Akt), which is involved in regulating the estrogen receptor. AstraZeneca, for one, is testing its Akt inhibitor, ...

In a study published in PNAS, a research team has resolved the first high-resolution structure of the sgc8c DNA aptamer that targets protein tyrosine kinase 7 (PTK7), engineered two optimal sgc8c ...

Lipid kinases are enzymes that play a critical role in both cell signaling and membrane trafficking by phosphorylating lipid ...

Detailed price information for Eli Lilly and Company (LLY-N) from The Globe and Mail including charting and trades.

Receptor tyrosine kinases (RTKs) regulate many critical biological processes such as cell growth, differentiation, and survival through the recruitment of intracellular signaling molecules. The ...

Receptor protein tyrosine phosphatases are cell membrane-localized proteins. They are regulators of cell–cell contacts and are also considered likely to be tumor suppressors but how they ...