Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the ...

Kodi Ravichandran (VIB-UGent Center for Inflammation Research) and colleagues found that pyroptosis, a form of programmed ...

In total, 39 differentially expressed pyroptosis genes were identified by comparing normal and tumor samples. Correlation analysis revealed 933 pyroptosis-related lncRNAs. Furthermore, univariate Cox ...

Pyroptosis components increase the proliferative and migratory abilities of lung cancer cells, but also promote an anti-tumor immune microenvironment," remarks Dr. Zhou.

Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the cancer more resistant to treatment, according to new research from ...

Caspase-1 triggers programmed necrosis called pyroptosis by gasdermin-D (GSDMD) cleavage. GSDMD-deficient cells are, however, susceptible to caspase-1-mediated cell death. Researchers at Kanazawa ...

To counteract, host cells undergo pyroptosis via initiating receptor-interacting serine/threonine-protein kinase 1 (RIPK1)–dependent caspase-8–directed gasdermin D (GSDMD) cleavage.

Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the ...

The study shows that the Western Diet could increase the sensitivity of IBD onset through DCA-induced Gsdme-mediated pyroptosis via the DCA-S1PR2 pathway, leading to disruption of the IEC barrier.

ABOVE: ISTOCK.COM, MELETIOS VERRAS C ytokine release syndrome, a side effect of an immunotherapy used to treat leukemia and lymphoma, appears to be caused by the way the intervention kills the tumor ...