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Regulatory T cells suppress CD4+ effector T cell activation by controlling protein synthesis. Journal of Experimental Medicine, 2023; 220 (3) DOI: 10.1084/jem.20221676; Cite This Page: MLA; APA; ...
Celiac disease is also a good candidate for regulatory T-cell therapy because in more than 90% of patients it is caused by a genetic variant called HLA-DQ2.5, Muller added.
Regulatory T cells (TReg cells) are a special subset of T cells that prevent other immune cells from attacking the body’s own tissues and other harmless environmental materials, such as food and ...
A regulatory class of human T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity, according to a new study led by Children's ...
Regulatory T cells contribute to physiological homeostasis. These cells improve insulin sensitivity and lipid breakdown in fatty tissues, improve muscle repair, and promote cell differentiation in ...
A study by Children’s Hospital of Philadelphia (CHOP) researchers has found that a class of human regulatory T cells descends from two different origins, one that relates to autoimmunity and one ...
Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA. Proceedings of the National Academy of Sciences, 2024 , 121 (23 ...
More information: Miguel Marin-Rodero et al, The meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis, Science Immunology (2025). DOI: 10.1126/sciimmunol.adu2910 ...
Regulatory T cells, or Tregs, play a key role in modulating other cells in the immune system so they don't attack the body’s own tissues. The failure of Tregs can lead to autoimmune diseases.
Egle Therapeutics to Highlight Novel Preclinical Findings for Regulatory T Cells Targeting Programs EGL-001 and EGL-002 With Poster Presentations at the 2025 AACR Annual Meeting.