By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

When ribosomes go rogue Unusual variations in the cellular protein factory can skew development, help cancer spread, and more. But ribosome variety may also play biological roles, scientists say.

Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But a critical aspect underlying the machinery of protein manufacture has long ...

Researchers have deciphered the structure of part of the ribosome found in mitochondria, the power plants of the cell. The scientists were able to benefit from advancements in the field of ...

The results also will help researchers tease out further details of the ribosome’s structure and function, information that may be useful in the design of new antibiotics.

Scientists have evidenced, at the atomic scale, the three-dimensional structure of the complete human ribosome and the detailed interactions that occur within it. These findings open the way to ...

The structure of the yeast ribosome is shown with the large rRNA subunit in yellow, the small rRNA subunit in light blue, additional eukaryote-specific rRNA segments in red, and accessory proteins ...

Structure determination with obstacles Until now, the molecular structure of the ribosomes found in mitochondria, the power plants of the cell, was still largely unknown.

A figure of the 80S ribosome structure. This image relates to an article that appeared in the Nov. 26, 2010, issue of Science, published by AAAS. The study, by Dr. Adam Ben-Shem at IGBMC (Institut ...

The recent success in ribosome structure determination by cryoEM has opened the door to defining structural differences between ribosomes of pathogenic organisms and humans and to understand ...

A ribosome is an intercellular structure made of both RNA and protein, and it is the site of protein synthesis in the cell. The ribosome reads the messenger RNA (mRNA) sequence and translates that ...