In addition to their ability to directly inflict damage on macromolecules, ROS and RNS indirectly induce damage to tissues by activating a number of cellular stress-sensitive pathways. These ...

a key player in this pathway, can prevent chemotherapy-induced cell death. These results, published in Nature, could help pinpoint treatment-resistant tumors. Low concentrations of ROS are required ...

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

However, activating a specific ROS dependent signaling pathway in the cells restored IL-10 release, according to the study.

Site-specific ROS inhibitors as potential therapeutic targets. The identification of redox signaling pathways that contribute to muscle contractile dysfunction may provide potential new targets for ...

Researchers focused on a pathway that harnesses reactive ... Low concentrations of ROS are required for normal cell signaling, but higher levels of ROS can damage cells and contribute to diseases ...

Researchers focused on a pathway that harnesses reactive ... Low concentrations of ROS are required for normal cell signaling, but higher levels of ROS can damage cells and contribute to diseases ...