Calcium-uptake and ATPase studies carried out on fragmented sarcoplasmic reticulum from muscle of patients with Duchenne dystrophy showed low initial and total calcium uptake, low ATPase activity a ...

The sarcoplasmic reticulum (SR) is a specialised organelle in skeletal muscle fibres that plays a pivotal role in regulating calcium dynamics crucial for muscle contraction and relaxation.

The myofibrils occupy a large cell volume and are surrounded by cisternae of the smooth endoplasmic reticulum (or sarcoplasmic reticulum), which stores the calcium essential for muscle contraction.

The myofibrils occupy a large cell volume and are surrounded by cisternae of the smooth endoplasmic reticulum (or sarcoplasmic reticulum), which stores the calcium essential for muscle contraction.

Even when the primary calcium channels in the smooth muscle cells were blocked, Piezo1 provided an alternative contraction pathway that helped maintain some muscle function.

Muscle contraction is known to be regulated by calcium. An action potential generated by a motor neuron propagates on the muscle cell surface, activates voltage-gated calcium channels and allows ...

As food is digested and nutrients are absorbed, there is a lot of movement in the gut. Scientists have now shown that a ...

This in turn sparks off a more massive calcium ion release from the sarcoplasmic reticulum (SR) calcium ion storage complex, through other channels, the SR-calcium ion release channel.

Skeletal muscle contraction is activated through voltage dependent release of Ca2+ from the intracellular storage location, the sarcoplasmic reticulum (SR) through ryanodine receptors (RyR). Ca2+ ...