Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
Autophagy has long been considered as a physiological process solely for degradation, but its secretory role has recently emerged. A group of researchers, including Tomonori Kimura, a researcher at ...
Scientists at Umeå University in Sweden report that they can now show how the poliovirus behaves when it takes over an infected cell and tricks the cell into producing new virus particles. Polio was ...
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
Enteroviruses are non-enveloped positive-sense RNA viruses that cause diverse diseases in humans. Their rapid multiplication depends on remodeling of cytoplasmic membranes for viral genome replication ...
TJS and JB are listed as inventors on a related patent, PCT/AU2020/050908 for measurement of autophagy in humans. “The anti-aging MIRACLE.” “Strengthen your immune system.” “Lose weight fast.” These ...
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