Proceedings of the National Academy of Sciences of the United States of America, Vol. 78, No. 1, [Part 2: Biological Sciences] (Jan., 1981), pp. 318-322 (5 pages) The pituitary cell line, AtT-20, ...

This is a preview. Log in through your library . Abstract Organelles are not uniformly distributed throughout the cytoplasm but have preferred locations that vary between tissues and during ...

Syndromes caused by insufficient secretion of peptide hormones originate either from an inadequate population of endocrine secretory cells or from deficiencies in the secretory process. Two remarkable ...

A medullary carcinoma of the thyroid gland was examined by electron microscopy, histochemistry and bioassay for thyrocalcitonin. Numerous secretory granules were present in the cytoplasm of the ...

† Most-abundant zymogen granule proteins. ‡ Different isoforms present in zymogen granules. § Validated by morphological studies after identification by mass spectrometry. As the molecular mechanisms ...

Though it remains a prime pathological hallmark of Alzheimer disease, Aβ amyloid has yet to convincingly prove itself as the major toxic species driving AD. Until such evidence emerges, some ...

In their experiment, the researchers labelled the secretory granules of Drosophila salivary gland cells both green and magenta. Normally, the secretory granules are of the right size, are well ...

We have known for a long time that cells break down their own materials as they wear out. All these processes are called cellular self-digestion (autophagy). Researchers at ELTE have now observed in ...

In diabetes research over the past two decades, Anath Shalev, M.D., has shown that the protein TXNIP regulates survival and function of beta cells, the pancreatic cells that produce the hormone ...

† Most-abundant zymogen granule proteins. ‡ Different isoforms present in zymogen granules. § Validated by morphological studies after identification by mass spectrometry. As the molecular mechanisms ...