This segment tells the story of a genetic mutation affecting the population of West Africa. Although helpful in preventing malaria, this mutation can also lead to sickle cell anemia.

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

Sickle Cell Disease is an awful genetic disease that disproportionally affects black people. It's caused by a single-point mutation in DNA, which results in a modified hemoglobin protein, differing by ...

These other forms of sickle-cell disease are compound heterozygous states in which the person has only one copy of the mutation that causes HbS and one copy of another abnormal haemoglobin allele.

Sickle cell disease is a group of inherited disorders that affect the hemoglobin, which causes sickle-shaped red blood cells. Learn about the symptoms, causes and treatment.

Some doctors told him he'd live with the disease forever, but Khaled Alsheebani never stopped believing treatments would advance one day.

The thorny history of sickle cell anemia As part of the university's Racism and Repair in the Modern Academy project, Johns Hopkins researchers look inward at the past, present, and future of ...

UCSF Benioff Children's Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease.

Though Beauzile is the first in New York to successfully undergo sickle cell anemia-curing gene therapy, he's preceded by Kendric Cromer, a 12-year-old boy from Washington, DC who received ...

A new type of bone marrow transplant can cure sickle cell disease with only half of the donor's cell proteins matching, according to new clinical trial results published in the New England Journal ...

The first gene therapy treatment for sickle cell disease has been approved in the U.K. , a move that could offer relief to thousands of people with the disease.

The first healthy volunteer has been dosed in a Phase 1 study of Cellarity's novel globin-switching therapy CLY-124 for ...