Sphingolipid structure and metabolism. Ceramide consists of a sphingosine long-chain base (LCB) and an amide-linked fatty acyl chain that varies from 14 to 26 carbons (C) in length 1,2 ...

Sphingolipids are ubiquitous building blocks of eukaryotic cell membranes. Progress in our understanding of sphingolipid metabolism, state-of-the-art sphingolipidomic approaches and animal models ...

A team of MUSC researchers report in Frontiers in Immunology that they have identified a type of fat known as a sphingolipid that could predict the severity of heart disease in African American ...

Researchers say study results point to the "high therapeutic potential" of targeting the sphingolipid synthesis pathway as a strategy against muscular dystrophy. genprowebdirectory ...

Researchers at the Medical University of South Carolina discover a potential sphingolipid biomarker that predicts severity of heart disease in African American lupus ...

The synthesis and degradation of sphingolipids by mixed peripheral leukocytes from four patients with the Chediak—Higashi syndrome were studied in vitro. Incorporation of glucose uniformly ...

A team of researchers is the first to associate neuronal activity to the levels of sphingolipids, a type of fat, in brain cells. Furthermore, disruption of sphingolipid metabolism led to ...

This study revealed a previously unknown connection between high temperature exposure and sphingolipid metabolism in obesity, suggesting that HT can ameliorate IR by promoting sphingolipid ...

Furthermore, disruption of sphingolipid metabolism led to significant neuronal damage and neurodegeneration in animal models, revealing a new molecular perspective to the cause of Gaucher's disease.

Sphingolipid fingerprint predicts heart disease severity in African American lupus patients. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2021 / 08 / 210816161346.htm ...