Researchers at New York City-based Mount Sinai Health System have identified distinct biological markers in patients with mild Crohn’s disease, potentially paving the way for more personalized and ...

Ceramide is considered to be the central hub of sphingolipid metabolism, and is synthesized de novo from the condensation of palmitate and serine to form 3-keto-dihydrosphingosine (not shown). In ...

A new study led by researchers at Mount Sinai Health System has identified distinct biological signatures in patients with mild Crohn’s disease, offering a potential pathway toward more personalized ...

Sphingolipid metabolism may therefore be an important target for therapeutic development for neurological disorders associated with mutations in membrane trafficking. "We are cautiously optimistic ...

Munich news, health insurance, technology, jobs and other topics for expatriates. The Eye Newspapers covers daily news and offers services for foreigners.

Disruptions in brain sphingolipid metabolism reveal new insights into cause of Gaucher disease. ScienceDaily . Retrieved May 20, 2025 from www.sciencedaily.com / releases / 2022 / 07 ...

The synthesis and degradation of sphingolipids by mixed peripheral leukocytes from four patients with the Chediak—Higashi syndrome were studied in vitro. Incorporation of glucose uniformly ...

This study revealed a previously unknown connection between high temperature exposure and sphingolipid metabolism in obesity, suggesting that HT can ameliorate IR by promoting sphingolipid ...

Researchers resent a new molecule for visualizing the sphingomyelin metabolism. This offers prospects for innovative therapeutic approaches in infection research. At the end of the 19th century ...

The findings, published in Cell Metabolism on November 14, 2024, open an entirely new avenue of potential drug targets to address these diseases and adverse health events like stroke or heart attacks.

Furthermore, disruption of sphingolipid metabolism led to significant neuronal damage and neurodegeneration in animal models, revealing a new molecular perspective to the cause of Gaucher’s disease.