By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

Researchers have deciphered the structure of part of the ribosome found ... RNA accounts for just under a third of the entire complex. One reason for this is that the RNA molecules have shortened ...

With a new mapping tool, Princeton engineers have revealed how a factory inside cells builds ribosomes, the machinery ...

This new RNA repair complex is a 270-kDa heterohexamer composed of three proteins—Pnkp1, Rnl and Hen1—that are required to repair ribotoxin-cleaved RNA in vitro. The crystal structure of the ...

How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where ...

Once dismissed as “junk,” a group of RNA molecules has been found to help regrow damaged nerves in mice in new research. The ...

And in eukaryotes (life forms with complex cells like ours) there is plenty of extra RNA sticking out of the ribosomes, like the tentacles of a sea anemone. “We think this may provide a ...