An increasing array of B-cell targeting approaches may aid clinicians in managing the cycles and flares of lupus, according ...

The aberrant activation of B cells plays a central role in the pathogenesis of various autoimmune diseases and B-cell lymphomas. Now, Honigberg and colleagues describe an orally available ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...