The molecular basis of phospho-tyrosyl-regulation of Src-family and Syk-family protein tyrosine kinases in signaling pathways is a current focus of the lab. The conformational activation of Src kinase ...

The MPS is involved in various cellular processes, such as inter- and intracellular signaling ... Macarrón-Palacios to investigate the neural cytoskeleton in his doctoral thesis.

For this reason, this matter has recently brought a lot of attention for the development of drugs targeting the BCR signaling pathway. Fostamatinib disodium is the first Syk inhibitor available ...