Transforming growth factor-beta (TGF-β)/bone morphogenic protein (BMP) signaling is involved in the vast majority of cellular processes and is fundamentally important during the entire life of ...

Transforming growth factor-β (TGF-β) signaling plays a vital role in regulating cell growth, differentiation, and development in a wide array of biological systems.

Citation: TGF-β signaling pathway mediates neuronal-intestinal mitochondrial stress response and lipid metabolism, finds study (2024, October 24) retrieved 12 July 2025 from https://medicalxpress ...

A tale of two signaling pathways: TGF-Beta and RAS. On its own, TGF-beta—a type of signaling protein known as a cytokine—is not an ideal drug target.

A Tale of Two Signaling Pathways: TGF-Beta and RAS. On its own, TGF-beta — a type of signaling protein known as a cytokine — is not an ideal drug target.

Two new mouse models of uterine cancer reveal that the TGF-beta signaling pathway in uterine cells protects against the disease by suppressing the overgrowth and oncogenesis of the endometrium ...

Background: TGF-beta acts both as a tumor suppressor or tumor promoter depending upon cellular context and stage of tumor progression. TGF-β exerts its effects through the TGF-beta-R1/ R2 receptors ...

“The TGF-beta signaling pathway regulates the development of many types of cancer, but it was not clear whether it also played a role in uterine cancer development,” said corresponding author Dr.

"The TGF-beta signaling pathway regulates the development of many types of cancer, but it was not clear whether it also played a role in uterine cancer development," said corresponding author Dr ...

New interactions uncovered affecting TGF-beta pathway in humans. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2015 / 12 / 151221071627.htm.

For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once ...