A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they ...

The analysis of the involvement of crisis in tumorigenesis has been aided by genetically defined cancer-prone mice that lack telomerase activity. These mouse models have provided insights into the ...

Telomerase binds to the G-tail of the telomere ... and new insights into telomeres and their role in aging and cancer appear regularly in the scientific literature. One thing is clear, however ...

Telomerase is a ribonucleoprotein enzyme responsible for maintaining ... 8 The observed association between shorter telomeres and increased risk of cancer, cardiovascular disease, and ...

Having determined how telomerase is recruited ... shelterin complex involved in telomere maintenance and implicated in cancer ...

Their findings pave the way for new therapeutic approaches targeting telomerase, an enzyme implicated in cancer progression. Colorectal cancer, which affects the colon or rectum, is the third most ...

The laboratory is using or has plans to use many cutting-edge technological developments in cancer and aging genetics and translational research such as RRBS-seq and Single-cell epigenomics. Studies ...

Inhibiting telomerase activity ... that lower-risk MDS is a progressive blood cancer with high unmet need, where many patients with anemia become dependent on red blood cell transfusions, which ...