Then, during the next round of DNA replication, DNA polymerase and the DNA repair enzymes fill in the other strand. Thus, telomerase is able to both maintain and extend the length of telomeres.

A type of virus thought to be a "mere curiosity" is plentiful in one common bacteria, and possibly others, a Monash ...

Researchers discovered that telomere phage is surprisingly common in Klebsiella, a type of bacteria that can cause pneumonia ...

Furthermore, telomere shortening due to the inability of the DNA-replication machinery to fully replicate the ends is a critical mechanism of tumor suppression as well as a hallmark of aging.

This experiment showed that the biochemical machinery involved in telomere replication had to be very broadly conserved, and opened the door to studies of telomere biochemistry and genetics in yeast ...

5 This checkpoint is important to prevent cells from replicating damaged DNA. Due to this phenomenon, scientists describe telomere length as a biological clock that indicates the lifespan of a cell ...

Researchers, led by Penn State biologists, have comprehensively predicted the location of potential non-B DNA structures in ...

When organisms encounter problems—what scientists call "replication stress"—this process ... extend their lifespans by ...

(C) ssDNA is also generated at telomeres and is a signal of telomere instability. A common feature in all of these structures is the presence of ssDNA, which causes ATR activation to promote RF ...

I am studying the protein complex CST which is essential in Telomere replication and upkeep, as well as having functions more broadly in DNA replication and repair. I am interested in how the ...

A type of virus thought to be a ‘mere curiosity’ is plentiful in one common bacteria, and possibly others, a Monash ...