As bioequivalence had to be shown with 2 reference products sample size was adjusted to 3 x 18 (54) subjects. Therefore 60 patients were included to allow a drop-out of 10% (6 subjects).

Cite this: Are Bioequivalence Studies of Levothyroxine Sodium Formulations in Euthyroid Volunteers Reliable? - Medscape - Mar 01, 2004. Abstract and Introduction ...

Experiencing a lack of any of the study’s five types of social connection — to any degree — was associated with higher risk of dying early from any cause, the authors found.

Bioequivalence studies are an essential component in the development and approval of generic pharmaceutical products, ensuring that they perform similarly to their reference counterparts.

The Department of Veterans Affairs has launched a study to determine whether three types of cancer are linked to environmental exposures for U.S. troops who served in Iraq, Afghanistan and elsewhere.