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tyrosinase, and TPTE – that are designed to stimulate an immune response against the cancer. Around 90% of all cases of melanoma affecting the skin express at least one of those antigens ...
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Oncept contains a gene encoding human tyrosinase, an enzyme associated with skin pigmentation ... respond,” says Christian Ottensmeier, a Cancer Research UK investigator at Southampton University.
Tyrosinase is found in melanocytes, which are specialized skin cells that produce the ultraviolet absorbing pigment, melanin. In the presence of sunlight, tyrosinase stimulates melanin production.