BYU boasts the second-best defense in the country, allowing just 205.3 yards per game, while Colorado’s defense ranks 112th.

Wideout Sincere Brown headlines Colorado’s offensive weapons, as the Campbell/USF transfer is averaging 29.0 yards per catch to go with two touchdowns. Defensively, Colorado has allowed 22.5 points per game, but in Power Four showdowns with Georgia Tech and Houston, the Buffaloes surrendered 27 and 36 points.

Colorado and BYU will meet in Week 5 of the 2025 college football season. Here's how to watch, including start time, TV channel:

Series History: CU leads 8-4-1, but lost last three matchups, including 36-14 in last year’s Alamo Bowl

Last year, both CU and BYU shared nearly the same exact fate. They were stuck in a four-way tie with Iowa State and Arizona State to see who would play in the Big 12 Championship game. Every team was tied at 7-2 in conference play, with CU and BYU taking that even further, posting the same home record, 4-1, and away record, 3-1, as each other.

Last December, in the Valero Alamo Bowl, BYU defender Isaiah Glasker made national headlines after intercepting Shedeur Sanders late in the fourth quarter. As he popped up from his diving pick near the sideline, Glasker broke into a rendition of Deion “Coach Prime” Sanders’ iconic celebration dance.

East Carolina has one of the best passing offenses in the country, with efficient senior quarterback Katin Houser throwing the ball around 40 times per game. The Pirates are also tied for fourth nationally with 10 sacks as a team and are just outside the top 10 in scoring defense (nine points allowed per game).