Leiden researchers have discovered an enzyme that helps bacteria feed on everyday plastics. This common enzyme could play a ...

Cofactors enable enzymes to bind their substrates; similarly, my roommate’s willingness to listen, advise, commiserate and celebrate encouraged me to open myself up to new opportunities during my ...

Instead of stabilizing its functional form, the mutated enzyme tends to disrupt communication between the cofactor and the ...

A peptide bridge is designed to construct a fusion enzyme with electrostatic cofactor channeling, reducing NADPH input by two orders of magnitude or decreasing reaction time threefold with&nbsp ...

Many enzymes require cofactors such as nicotinamide adenosine dinucleotide (NAD+) or nicotinamide adenosine dinucleotide phosphate (NADP+) to shuttle electrons between reactions.

Little is currently known about the molecular determinants of energy barriers along enzyme catalytic pathways. Kern and co-workers have studied this question in adenylate kinase (Adk) and now ...

Now, a team of researchers has developed a microreactor that efficiently regenerates cofactors through enzyme-catalyzed reactions.

Researchers have identified how such a cofactor, the so-called hydrogen cluster, is assembled. Specifically, they describe the previously unexplained role of the enzyme HydF, which is involved in ...

Osaka University scientists describe a novel protein that spurs the post-translational modifications of the amino acid tryptophan to create an enzyme cofactor. This work may lead to the creation ...

Confining the enzymes and the cofactor in the porous nanoparticles overcomes this challenge because it produces stable, reusable catalytic nanoparticles. “Researchers are devoting much attention these ...

Researchers at UC Santa Barbara, UCSF and the University of Pittsburgh have developed a new workflow for designing enzymes from scratch, paving the way toward more efficient, powerful and ...