A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators.

A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, ...

During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

mRNA display is particularly suitable for such purpose. [69] To perform the selection, the mRNA-displayed peptide or protein library is first incubated with a target protein of interest (Figure 1).

Once injected, these mRNA molecules enter the cytoplasm of host cells, where ribosomes translate them into antigenic proteins. These proteins are then displayed on the cell surface, triggering ...

METHODS: In biochemist David Giedroc’s lab at Texas A&M University, Cornish studied how ribosomes translate mRNA into proteins, focusing his graduate work on frameshifting, ... Lab safety rules ...

Bin Wu, associate professor in the department of Biophysics and Biophysical Chemistry at the School of Medicine, visited ...