However, it is not known how this motif confers control by mTOR or how mTOR modulates their translation. mTOR is also reported to regulate the transcription of rDNA genes (genes encoding ribosomal ...

Right: mTOR promotes MAPKAPK2 translation during senescence, thereby inhibiting the AMD activity of ZFP36L1, which targets some SASP components. Full size image. In a separate study, ...

Ketamine's antidepressant actions depend on the drug's ability to affect mRNA translation, researchers reported in the December 17, 2020, issue of Nature. The work narrows down the molecular ...

Several studies have shown that mTOR is a crucial pathway for cell cycle progression, translation, transcription, differentiation, apoptosis, and many other physiological processes.

Egyptian online auto parts marketplace Mtor has raised $2.8 million in pre-seed investment led by Egypt-focused venture capital firm Algebra Ventures. Other investors that participated in the ...

The results suggested that mechanistic target of rapamycin (mTOR) inhibition is a potential therapeutic avenue for sarcoidosis, which the authors said should be explored in larger clinical trials.

The serine-threonine kinase mammalian target of rapamycin (mTOR) plays a major role in the regulation of protein translation, cell growth, and metabolism. Alterations of the mTOR signaling pathway are ...

As the cell's molecular control center, the mTor kinase regulates cellular metabolism, growth and division. However, in cells affected by pathological change, the regulation goes awry. Scientists ...

Dr Marla Lipsyc-Sharf discusses how to best manage the challenging side effects associated with PIK3CA and mTOR Inhibitors to optimize patient care. News & Perspective Tools & Reference CME/CE.

mTOR stands for mammalian/mechanistic target of rapamycin. Rapamycin is an immunosuppressant drug that was first isolated from a bacterium found on Easter Island in the mid-20th Century.

Background: Although improvements in the treatment of ovarian cancer have increased the global prognosis, the metastatic disease is still an incurable situation. Therefore, it is necessary to identify ...