Ulke J, Chopra S, Kadiri OL, et al. PTPRJ is a negative regulator of insulin signaling in neuronal cells, impacting protein biosynthesis, and neurite outgrowth. J Neuroendocrinol . Published ...

Insulin orchestrates blood glucose levels by signaling fat and muscle cells to absorb the sugar and liver cells to stop pumping it out, so most research on insulin signaling focuses on these tissues.

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study.

New insights into insulin action: Dynamic signaling network offers therapeutic approaches for type 2 diabetes Peer-Reviewed Publication Deutsches Zentrum fuer Diabetesforschung DZD ...

Insulin signaling pathways remained comparable between the THΔper and wild-type mice. Improved insulin sensitivity in THΔper mice was independent of any changes in cellular insulin signaling.