Reveals a role for mTORC2 in neutrophil chemotaxis. Nature Reviews Molecular Cell Biology ... (MLC), which are partly mediated by RHOA-activated RHO-associated kinase (ROCK).

mTORC2 is aberrantly activated in cancer and therefore is considered to be an important therapeutic target. The hedgehog pathway, which is also often hyperactivated, regulates transcription of ...

New results from researchers at MedUni Vienna's Center for Pathobiochemistry and Genetics show that a protein called mTORC2, which is the target of newly developed cancer drugs, is not even active ...

Aliad Biopharma discovers new mTORC2 inhibitors for Alzheimer’s disease. Oct. 24, 2024. Aliad Biopharma Co. Ltd. has described compounds acting as autophagy inducers and mTOR complex 2 (mTORC2) ...