New research has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the ...

Moreover, our results of the integration of cAMP-PKA pathway with nuclear receptor-mediated signaling during ATRA-induced APL cells maturation further support the major role of a cytosolic signal ...

Fruit fly mutants that have severe sleep deficits perform better at olfactory learning and memory tasks, according to a study published in the open-access journal PLOS Biology by Sheng Huang and ...

It’s called the cAMP/PKA signaling pathway for its two main actors — cAMP (cyclic adenosine monophosphate) and PKA (cAMP-dependent protein kinase).

Investigating conserved signaling pathways in different cell types shows that memory is not a unique property of neurons.

Researchers discover that the phosphorylation of a newly identified protein kinase substrate downstream of the dopamine signaling pathway regulates the brain reward behavior.

A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously ...