In addition to the dimer, the structure also reveals that the protease's C-terminal leucine residue is "stuffed into the active site," Rice says, effectively turning off the enzyme after it ...

Q: You’ve solved the first structure of an intramembrane protease. What does the rhomboid structure tell us about this type of enzyme in general? A: I think the main implication is, first of all, that ...

The structure of enzymes determines how they control ... "The type of biochemical reactions and how they occur depends on the structure of the proteins," says Prof. Dr. Olav Schiemann from the ...

“We want to predict the functions of all proteins so that we can know all the proteins a cell has and better study or engineer the whole cell for biotechnology or biomedical applications.” Reference: ...

The enzyme, known as HIV-1 protease, ... This is a 3-D structure of the HIV-1 protease in cartoon representation with bound clinical drug darunavir (shown as sticks).

The crystal structure of the XMRV protease differs from the structures of other retropepsins and instead resembles those of pepsin-like enzymes, suggesting that this protease may represent a ...

Structure Of Enzyme In Unusual Virus Identified Date: September 20, 2007 Source: ... In contrast, many viruses commandeer the genes of host cells to make enzymes and proteins, ...

Scientists learn structure of enzyme in unusual virus WEST LAFAYETTE, ... which is needed to produce structural proteins that are assembled to create the outer shells, or capsids, for new virus ...

This image shows changes in the 3-D structure of the original protein scaffold (left) upon directed evolution of the scaffold to the artificial RNA ligase enzyme (right).

First structure of key COVID enzyme at human body temperature Subtle structural changes in virus's 'main protease' over a range of temperatures may point to new targets for antiviral drugs ...